Motif ID: FOS_FOS{B,L1}_JUN{B,D}.p2

Z-value: 3.358


Transcription factors associated with FOS_FOS{B,L1}_JUN{B,D}.p2:

Gene SymbolEntrez IDGene Name
FOS 2353 v-fos FBJ murine osteosarcoma viral oncogene homolog
FOSB 2354 FBJ murine osteosarcoma viral oncogene homolog B
FOSL1 8061 FOS-like antigen 1
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

GenePromoterPearsonP-valuePlot
JUNDchr19_-_18253048-0.523.7e-02Click!
FOSchr14_+_748152330.448.6e-02Click!
JUNBchr19_+_12763295-0.263.2e-01Click!
FOSBchr19_+_50663089-0.224.0e-01Click!
FOSL1chr11_-_654243850.136.3e-01Click!


Activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2.

activity profile for motif FOS_FOS{B,L1}_JUN{B,D}.p2


Sorted Z-values histogram for motif FOS_FOS{B,L1}_JUN{B,D}.p2

Sorted Z-values for motif FOS_FOS{B,L1}_JUN{B,D}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOS_FOS{B,L1}_JUN{B,D}.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_116099648 9.446 NM_000245
NM_001127500
MET

met proto-oncogene (hepatocyte growth factor receptor)

chr7_-_135083906 7.197 NM_205855
FAM180A
family with sequence similarity 180, member A
chr16_+_56219802 6.917 NM_001145771
NM_001145772
NM_001145773
NM_201524
NM_201525
GPR56




G protein-coupled receptor 56




chr19_-_40711034 6.686 NM_001166034
NM_001166035
NM_198538
SBSN


suprabasin


chr5_+_150000394 6.429 NM_001109974
NM_007286
SYNPO

synaptopodin

chr1_+_17719405 6.332 ARHGEF10L
Rho guanine nucleotide exchange factor (GEF) 10-like
chr1_+_181421984 6.099 LAMC2
laminin, gamma 2
chr6_+_31190505 5.860 NM_014068
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr1_-_94779727 5.505 NM_001178096
NM_001993
F3

coagulation factor III (thromboplastin, tissue factor)

chr2_+_169634330 5.384 DHRS9
dehydrogenase/reductase (SDR family) member 9
chr12_-_68369322 5.320 NM_152439
BEST3
bestrophin 3
chr6_-_138470160 5.153 NM_022121
PERP
PERP, TP53 apoptosis effector
chr1_+_245646080 4.931 NM_001079821
NM_001127461
NLRP3

NLR family, pyrin domain containing 3

chr4_+_154397975 4.654 TRIM2
tripartite motif containing 2
chr17_-_36469869 4.497 NM_001165252
LOC730755
keratin associated protein 2-4-like
chr4_+_169989680 4.462 NM_001166110
PALLD
palladin, cytoskeletal associated protein
chr17_-_37022465 4.440 NM_005557
KRT16
keratin 16
chr4_+_108965167 4.423 NM_001136258
SGMS2
sphingomyelin synthase 2
chr5_+_140848905 4.257 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr4_+_120276386 4.253 NM_016599
MYOZ2
myozenin 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 8 of 8 entries
enrichment   p-value GO term description
5.96 4.34e-03 GO:0030574 collagen catabolic process
5.37 1.60e-03 GO:0032963 collagen metabolic process
5.10 8.69e-03 GO:0044243 multicellular organismal catabolic process
5.01 3.90e-03 GO:0044259 multicellular organismal macromolecule metabolic process
4.17 3.59e-02 GO:0044236 multicellular organismal metabolic process
2.52 2.52e-02 GO:0032496 response to lipopolysaccharide
2.44 8.83e-04 GO:0008544 epidermis development
1.35 2.73e-02 GO:0048513 organ development

Gene overrepresentation in compartment category:

Showing 1 to 6 of 6 entries
enrichment   p-value GO term description
6.56 5.44e-05 GO:0001533 cornified envelope
2.25 8.68e-03 GO:0005882 intermediate filament
2.08 2.43e-02 GO:0045111 intermediate filament cytoskeleton
1.42 8.68e-04 GO:0005856 cytoskeleton
1.42 3.39e-02 GO:0044421 extracellular region part
1.29 2.80e-02 GO:0005576 extracellular region

Nothing significant found in function category.